Figure 6: (A) The Alignment of structure of wild and mutated protein of spike SARS-Cov-2. (a) the whole trimer spike protein structure alignment with wild (green) protein and mutant at E484Q and L452R protein (Red). (b) Is represent the aligned image with surface structure (here green is A chain and gray is B chain (B) Detailed of results of molecular dynamics studies with the mutated protein with linoleic acids and two selected hits (Selexipag and pralatrexate). SARS-Cov-2 = Severe acute respiratory syndrome coronavirus-2