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Figure 1: Details of LA binding pocket: Three chains of spike protein (S1 region) form a compact trimer. LA binds to residues 408 and 409 of one chain (head region) and the other part of LA binds to the residues surrounding the hydrophobic pocket. LA: Red, A chain: Ribbon, B chain (surface). (a): LA bound to A and B chain, (b): More detailed close up view, (c): LA binding pocket at 90° of first view, (d): LA binding pocket from 180° of first view with head region residues interacting with residues 408 and 409 of the A chain, (e): LA bound to residues 408 and 409 on A chain and hydrophobic pocket can be seen in the chain B surrounding LA, (f): LA bound to residues 408 and 409 on A chain and hydrophobic pocket can be seen in the chain B surrounding LA. The residues in the hydrophobic pocket (green) can be seen surrounding LA. LA = Linoleic acid

Figure 1: Details of LA binding pocket: Three chains of spike protein (S1 region) form a compact trimer. LA binds to residues 408 and 409 of one chain (head region) and the other part of LA binds to the residues surrounding the hydrophobic pocket. LA: Red, A chain: Ribbon, B chain (surface). (a): LA bound to A and B chain, (b): More detailed close up view, (c): LA binding pocket at 90° of first view, (d): LA binding pocket from 180° of first view with head region residues interacting with residues 408 and 409 of the A chain, (e): LA bound to residues 408 and 409 on A chain and hydrophobic pocket can be seen in the chain B surrounding LA, (f): LA bound to residues 408 and 409 on A chain and hydrophobic pocket can be seen in the chain B surrounding LA. The residues in the hydrophobic pocket (green) can be seen surrounding LA. LA = Linoleic acid