Figure 5: (a) Ball and stick illustration for molecular interaction of receptor 3IRC (EDIII DENV-1) with RA ligand ZINC00899870, as predicted by MOE software. (b) 2D illustration for molecular interaction of receptor 3IRC (EDIII DENV-1) with RA ligand ZINC00899870, as predicted by MOE software. The hydroxyl group of ligand and Glut16 of receptor form a hydrogen bond, also, a pi-pi interaction is observed between the ligand and Lys15 residue of receptor. DENV: Dengue virus, EDIII=Envelope Domain III, RA=Rosmarinic acid, MOE=Molecular Operating Environment