Figure 4: Superimposed 3D structures of EDIII protein of four DENV serotypes (DENV-1, DENV-2, DENV-3 and DENV-4) using PyMOL software. The superimposition demonstrates overlapping between the beta sheets. Also, the low RMSD values calculated by the algorithm suggests very little deviation between the EDIII of four DENV serotypes, indicating highly conserved regions between them. DENV: Dengue virus, EDIII=Envelope Domain III, RMSD=Root Mean Square Deviation