Figure 4: Steps involved in the production of a chimeric antigen receptor: Step 1: Binding of the virus containing the gene for the chimeric antigen to the T-cell. Step 2: Entry of the virus into the T-cell and uncoating of the chimeric antigen gene. Step 3: Integration of the chimeric gene into the T-cell gene. Step 4: Transcription of the gene. Step 5: Protein expression