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Figure 2: Effect of SB365 on apoptosis in glioblastoma cells. (a and b) The induction of apoptosis by SB365 treatment was examined by DAPI and TUNEL staining, followed by imaging at ×400 magnification. Arrows indicate morphological features of apoptotic cells, such as fragmented and condensed nuclei in SB365-treated cells. (c) The expression of cleaved caspase-3 and cleaved poly (ADP-ribose) polymerase was determined by Western blotting in SB365-treated cells at the indicated doses for 72 h

Figure 2: Effect of SB365 on apoptosis in glioblastoma cells. (a and b) The induction of apoptosis by SB365 treatment was examined by DAPI and TUNEL staining, followed by imaging at ×400 magnification. Arrows indicate morphological features of apoptotic cells, such as fragmented and condensed nuclei in SB365-treated cells. (c) The expression of cleaved caspase-3 and cleaved poly (ADP-ribose) polymerase was determined by Western blotting in SB365-treated cells at the indicated doses for 72 h