Figure 2: Cellular architecture of tissues with time and dose of test compound 4308. The photographs. (a) fresh liver. (b-e) explants incubated without extracts of test compound for 2, 4, 8, and 24 h, (f-i) explants incubated with test compound 4308 (2 μg/ml) for 2, 4, 8, and 24 h. Cellular architecture of tissue was well conserved during the first 4 h (b, c, f and g) with gradual changes subsequently in the next 24 h