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Figure 3: (a) Control group showed normal architecture. (b) The doxorubicin group showed hepatocytes (arrow) with markedly foamy vacuolated cytoplasm (V), abnormal metaphase chromatin (star) and dilated sinusoids (S). (c) The doxorubicin and coenzyme Q10 groups showed intense microvacuoles (V). (d) The doxorubicin and Cynara scolymus L. groups showed variable-sized vacuoles (toluidine blue, scale bar = 5 μm)

Figure 3: (a) Control group showed normal architecture. (b) The doxorubicin group showed hepatocytes (arrow) with markedly foamy vacuolated cytoplasm (V), abnormal metaphase chromatin (star) and dilated sinusoids (S). (c) The doxorubicin and coenzyme Q10 groups showed intense microvacuoles (V). (d) The doxorubicin and <i>Cynara scolymus</i> L. groups showed variable-sized vacuoles (toluidine blue, scale bar = 5 μm)