Figure 1: (a) Immunohistochemical staining showing expression and localization of inducible nitric oxide synthase in normal control liver section. In the presented photomicrograph, inducible nitric oxide synthase immunoreactivity appears as light brown stain in hepatocytes and vascular endothelium. (b) Immunohistochemical staining showing expression and localization of inducible nitric oxide synthase in fructose enriched diet control liver section, inducible nitric oxide synthase immunoreactivity appears as dark brown stain in hepatocytes and vascular endothelium. (c) Immunohistochemical staining showing expression and localization of inducible nitric oxide synthase in rosiglitazone treated rats liver section. (d) Immunohistochemical staining showing expression and localization of inducible nitric oxide synthase in quercetin -treated rats liver section. (e) Immunohistochemical staining showing expression and localization of inducible nitric oxide synthase in rosiglitazone + quercetin -treated rats liver section