Indian J Pharm Close
 

Figure 2: (a) Cisplatin (0.5 mg/mL) and 10% dimethyl sulfoxide (DMSO) showed increased absorbance between 250 nm and 299 nm. Cisplatin (0.5 mg/mL) or 10% DMSO alone did not showed any characteristic increase in absorbance between 250 nm and 299 nm. Water used in the experiment also had no effect on cisplatin. (b) Continuous monitoring of cisplatin-DMSO adduct formation at every 5 min intervals for 30 min using ultraviolet spectrophotometer showed steady increase in the absorption between 250 nm and 299 nm

Figure 2: (a) Cisplatin (0.5 mg/mL) and 10% dimethyl sulfoxide (DMSO) showed increased absorbance between 250 nm and 299 nm. Cisplatin (0.5 mg/mL) or 10% DMSO alone did not showed any characteristic increase in absorbance between 250 nm and 299 nm. Water used in the experiment also had no effect on cisplatin. (b) Continuous monitoring of cisplatin-DMSO adduct formation at every 5 min intervals for 30 min using ultraviolet spectrophotometer showed steady increase in the absorption between 250 nm and 299 nm