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Figure 5: Effect of different concentrations of udenafil for 24 h on apoptosis in VEC and VSMC. Distributions of cells treated with different concentrations of udenafil displayed as dot plots: Viable cells (fluorescein isothiocyanate (FITC)/propidium iodide (PI)), apoptotic cells (FITC+/PI), secondary necrotic cells (FITC+/PI+). (a and f) Cells incubated with 0 μmol/l udenafil. (b and g) Cells incubated with 1 μmol/l udenafil. (c and h) Cells incubated with 10 μmol/l udenafil. (d and i) Cells incubated with 100 μmol/l udenafil. (e and j) Cells incubated with 1 mmol/l udenafil. A minimum of 10,000 events was counted per sample

Figure 5: Effect of different concentrations of udenafil for 24 h on apoptosis in VEC and VSMC. Distributions of cells treated with different concentrations of udenafil displayed as dot plots: Viable cells (fluorescein isothiocyanate (FITC)/propidium iodide (PI)), apoptotic cells (FITC+/PI), secondary necrotic cells (FITC+/PI+). (a and f) Cells incubated with 0 μmol/l udenafil. (b and g) Cells incubated with 1 μmol/l udenafil. (c and h) Cells incubated with 10 μmol/l udenafil. (d and i) Cells incubated with 100 μmol/l udenafil. (e and j) Cells incubated with 1 mmol/l udenafil. A minimum of 10,000 events was counted per sample