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Figure 3: Semiquantitative morphometric analysis of glomerular damage index. Figure summarizes the glomerular damage index (GDI) of animals in all the four groups. GDI was calculated on PAS stained sections at a magnification of ×400 with a scoring system of 0 to 4. 0 represents no lesion; 1+ represents sclerosis of <25% of the glomerulus; 2+ represents sclerosis of 25-50% of the glomerulus; 3+ represents 50-75% of the glomerulus and 4+ represents sclerosis of >75% of the glomerulus. Values represent the mean ± standard deviation (n = 4) of the samples. Signifi cant difference between Con and Dia groups: #p < 0.05; ##p < 0.01; ###p < 0.001. Significant difference between Dia and Dia+AMG, Dia and Dia+AGE groups: * p < 0.05; ** p < 0.01; *** p < 0.001

Figure 3: Semiquantitative morphometric analysis of glomerular damage index. Figure summarizes the glomerular damage index (GDI) of animals in all the four groups. GDI was calculated on PAS stained sections at a magnification of ×400 with a scoring system of 0 to 4. 0 represents no lesion; 1+ represents sclerosis of <25% of the glomerulus; 2+ represents sclerosis of 25-50% of the glomerulus; 3+ represents 50-75% of the glomerulus and 4+ represents sclerosis of >75% of the glomerulus. Values represent the mean ± standard deviation (<i>n</i> = 4) of the samples. Signifi cant difference between Con and Dia groups: #<i>p</i> < 0.05; ##<i>p</i> < 0.01; ###<i>p</i> < 0.001. Significant difference between Dia and Dia+AMG, Dia and Dia+AGE groups: * <i>p</i> < 0.05; ** <i>p</i> < 0.01; *** <i>p</i> < 0.001