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Figure 2: The expression of morphine tolerance. The analgesic effects of morphine (5 mg/kg test dose), morphine tolerant and saline group in both tail-fl ick (a) and hot-plate test (b). Each point represents the mean±SEM of percent of maximal possible effect (%MPE) for 6 rats. *P<0.001 compared to saline-treated group

Figure 2: The expression of morphine tolerance. The analgesic effects of morphine (5 mg/kg test dose), morphine tolerant and saline group in both tail-fl ick (a) and hot-plate test (b). Each point represents the mean±SEM of percent of maximal possible effect (%MPE) for 6 rats. *<i>P</i><0.001 compared to saline-treated group