Indian J Pharm Close
 

Figure 1: Pathogenesis for development of PAH and sites of drug action. Kv-voltage-gated potassium channels; ACE- angiotensin converting enzyme; PDE-phophodiesterase enzyme (Adapted from: Archer SL, Weir KE, and Wilkins MR. the Basic Science of Pulmonary Arterial Hypertension for Clinicians: new concepts and experimental therapies. Circulation. 2010 May 11; 121(18): 2045-2066)

Figure 1: Pathogenesis for development of PAH and sites of drug action. Kv-voltage-gated potassium channels; ACE- angiotensin converting enzyme; PDE-phophodiesterase enzyme 
(<i>Adapted from: Archer SL, Weir KE, and Wilkins MR. the Basic Science of Pulmonary Arterial Hypertension for Clinicians: new concepts and experimental therapies. Circulation. 2010 May 11; 121(18): 2045-2066</i>)