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Figure 1: Effect of 50% ethanolic extract of Achyranthes aspera on NDEA and CCl4 induced HCC. (a) Group I: Control animals show normal architecture. (b) Group II: NDEA + CCL4 induced cancer bearing animal shows neoplastic cells are arranged in lobules. (c) Group III: Administration of 50% ethanolic extract (100 mg/kg) of A. aspera (whole plant) on HCC bearing animals. Necrosis with malignant hepatocytes. (d) Group IV: Administration of 50% ethanolic extract (200 mg/kg) of A. aspera (whole plant) on HCC bearing animals. Liver shows the structure close to proximity of normal liver. (e) Group V: Administration of 50% ethanolic extract (400 mg/kg) of A. aspera (whole plant) on HCC bearing animals. Liver shows normal architecture of hepatocytes. |
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