Indian Journal of Pharmacology

Screening of medicinal plants for pharmacological actions: Importance of review of literature through WWW
J Mohanasundaram
November-December 2001, 33(6):460-460

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Behavioral actions of Myristica fragrans
Sonavane Ganeshchandra, Sarveiya Vikram, Kasture Veena, B Kasture Sanjay
November-December 2001, 33(6):417-424

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits 2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours. 3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

[ABSTRACT] Full text not available [PDF] [CITATIONS]

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Efficacy of atropine nasal aerosol spray against Organophosphorus poisoning
Kumar Pravin, R Vijayaraghavan, M Singh
November-December 2001, 33(6):431-436

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits 2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours. 3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

[ABSTRACT] Full text not available [PDF] [CITATIONS]

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Treatment of Helicobacter pylori infection- a review
Kate Vikram, N Ananthakrishnan
November-December 2001, 33(6):410-416

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits 2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours. 3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

[ABSTRACT] Full text not available [PDF] [CITATIONS]

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Fixed dose combinations and rational drug therapy
SC Pradhan, DG Shewade, S Ramaswamy, N Kastury, S Singh, KU Ansari
November-December 2001, 33(6):458-459

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Cardioprotective effects of acutely administered ramipril and losartan on myocardial infarct size in cholesterol-fed and salt-fed rats
A Annapurna, Babu M Rajendra, Reddy YSC Kesav, Kumar V Krishna
November-December 2001, 33(6):437-441

Seventeen antihistamines were studied far their effect on acetylcholine (Ach) Induced contraction of skeletal muscle (Skm) under Gaddum's superfusion technique. All drugs exhibit some degree of cuare like action In 0.1 to 10 mcg dose except in pheniramine, mabhydroline and metiamide where there was a regression of curarimimetic effect with increasing doses. During recovery from drug effect the tissue showed an increased sensitivity to the action of Ach. In some instances this potentiation was immediate. In high doses (100 mcg and above). some of the antihistamines produced contracture of Skm which was not blocked by curare.

[ABSTRACT] Full text not available [PDF] [CITATIONS]

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A method for evaluation of variables in drug interaction
Qing-Shan Zheng, Chang-Qing Gui, Rui-Yuan Sun
November-December 2001, 33(6):445-451

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits 2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours. 3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

[ABSTRACT] Full text not available [PDF]

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Placebos: Current status
Roy Vandana, Roy Tushar
November-December 2001, 33(6):396-409

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Effect of E.coli endotoxin induced fever on the pharmacokinetics and dosage regimen of cefuroxime in calves
RK Chaudhary, AK Srivastava, S Rampal
November-December 2001, 33(6):425-430

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits 2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours. 3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

[ABSTRACT] Full text not available [PDF] [CITATIONS]

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Effect of immu-21, a herbal formulation on granulocyte-macrophage colony stimulating factors, macrophage maturation and splenic plaque forming cells in experimental animals
S Chatterjee
November-December 2001, 33(6):442-444

1. The biochemical and haematological effects of tolmetin (a pyrole acetic acid derivative), on blood sugar,' serum cholesterol, serum uric acid, blood count, coagulation time, plasma fibrinogen content and euglobin clot lysis time (ELT) were studied in albino rabbits 2. Tolmetin (10 mg/kg), (P.O.) produced marked and significant hypoglycaemic, hypocholesterolaemic and hypouricaemic effects which started after one hour with a peak effect at two hours without complete recovery even upto four hours. 3. It decreased coagulation time and platelet count but increased plasma fibrinogen level and ELT.

[ABSTRACT] Full text not available [PDF] [CITATIONS]

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Immunostimulant profile of a polyherbal formulation RV08
babu M Rajendra, rao RV Krishna, A Annapurna, A Annapurna
November-December 2001, 33(6):454-455

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Pattern of drug use in hypertension in a tertiary hospital: A cross sectional study in the In-patient wards
Xavier Denis, Mathew Noby, Pradeep Johnson, Pais Prem
November-December 2001, 33(6):456-457

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Newer antineoplastic agents
R Balaraman
November-December 2001, 33(6):461-462

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Herbs on the net
Singh Jatinder
November-December 2001, 33(6):463-467

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Plagiarism: The new plague?
B Gitanjali
November-December 2001, 33(6):395-395

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A simple computer program for randomly allocating treatments
SC Chopra, C Gupta, S Arora
November-December 2001, 33(6):452-453

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