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Evaluation of CNS activity of Bramhi Ghrita
GS Achliya, SG Wadodkar, AK Dorle
Department of Pharmaceutical Sciences, Nagpur University Campus, Amravati Road, Nagpur - 440 033, India
Correspondence Address:
G S Achliya
Department of Pharmaceutical Sciences, Nagpur University Campus, Amravati Road, Nagpur - 440 033
India
OBJECTIVE: To eavaluate the CNS activity of Bramhi Ghrita, a polyherbal formulation containing Bacopa monneri, Evolvulus alsinoids, Acorus calamus, Saussurea lappa and cow«SQ»s ghee.
MATERIALS AND METHODS: The effect of Bramhi Ghrita on motor coordination, behavior, sleep, convulsions, locomotion and analgesia was evaluated in mice using standard procedures.
RESULTS: The formulation exhibited reduced alertness, spontaneous locomotor activity and reactivity. It also antagonized the behavioral effects of d-amphetamine, potentiated the pentobarbitone-induced sleep and increased the pain threshold. Bramhi Ghrita protected mice from maximum electroshock and pentylene tetrazole-induced convulsions.
How to cite this article:
Achliya G S, Wadodkar S G, Dorle A K. Evaluation of CNS activity of Bramhi Ghrita.Indian J Pharmacol 2005;37:33-36
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How to cite this URL:
Achliya G S, Wadodkar S G, Dorle A K. Evaluation of CNS activity of Bramhi Ghrita. Indian J Pharmacol [serial online] 2005 [cited 2023 Sep 29 ];37:33-36
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=2005;volume=37;issue=1;spage=33;epage=36;aulast=Achliya;type=0 |
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