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Year : 1995  |  Volume : 27  |  Issue : 1  |  Page : 34--36

Effect of nifedipine on glucose tolerance in normal volunteers and patients with diabetes mellitus

RN Chattopadhyay1, RK Roy2, S Mandal3, HL Lahiri4, SK Maitra5, MM Das6, HN Das7, TK Das8 
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Correspondence Address:
R N Chattopadhyay


Effect of nifedipine on glucose tolerance in normal volunteers and patients with diabetes mellitus was studied. Nifedipine (10 mg) produced no significant change on glucose tolerance in normal individuals, But in diabetic individuals, nifedipine produced a significant reduction in glucose tolerance at half an hour after glucose load. However, no such reduction was observed at one and two hours after glucose load. There is a possibility that nifedipine exerts inhibitory effect on insulin release specially in the initial phase in diabetic individuals but not in healthy volunteers.


How to cite this article:
Chattopadhyay R N, Roy R K, Mandal S, Lahiri H L, Maitra S K, Das M M, Das H N, Das T K. Effect of nifedipine on glucose tolerance in normal volunteers and patients with diabetes mellitus.Indian J Pharmacol 1995;27:34-36


How to cite this URL:
Chattopadhyay R N, Roy R K, Mandal S, Lahiri H L, Maitra S K, Das M M, Das H N, Das T K. Effect of nifedipine on glucose tolerance in normal volunteers and patients with diabetes mellitus. Indian J Pharmacol [serial online] 1995 [cited 2021 Nov 28 ];27:34-36
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1995;volume=27;issue=1;spage=34;epage=36;aulast=Chattopadhyay;type=0