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Year : 1994  |  Volume : 26  |  Issue : 3  |  Page : 194--199

In vitro studies on the effect of glycyrrhizin from Indian Glycyrrhiza glabra Linn on some RNA and DNA viruses

Badam Lalita 
 

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Badam Lalita


Glycyrrhizin a triterpeniod glycoside obtained from Glycyrrhiza glabra Linn., was tested against some RNA (Chandipura, Measles, Polio vaccine type 1,2 and 3, Polio wild type 1,2 and 3) and DNA (Herpes type 1 and 2) viruses. It inhibited plaque formation for HSV-1 and HSV-2 at a concentration of 0.606 mM. However with Chandipura, measles and polio types 1, 2 and 3 of both the wild and the Sabin«SQ»s vaccine strains, same effect could be obtained at a concentration of 1.216mM. The minimal inhibitory concentrations were not toxic to Vero (African Green Monkey kidney) and HeLa (Human Cervical carcinoma) cell lines.


How to cite this article:
Lalita B. In vitro studies on the effect of glycyrrhizin from Indian Glycyrrhiza glabra Linn on some RNA and DNA viruses.Indian J Pharmacol 1994;26:194-199


How to cite this URL:
Lalita B. In vitro studies on the effect of glycyrrhizin from Indian Glycyrrhiza glabra Linn on some RNA and DNA viruses. Indian J Pharmacol [serial online] 1994 [cited 2022 Oct 1 ];26:194-199
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1994;volume=26;issue=3;spage=194;epage=199;aulast=Lalita;type=0