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Year : 1994  |  Volume : 26  |  Issue : 2  |  Page : 141--143

Antidermatophytic activity of neem (Azadirachta indica) leaves in Vitro

Pankajalakshmi1, V Venugopal2, Taralakshmi3, V Venugopal4 
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Correspondence Address:
Pankajalakshmi


The antidermatophytic activity of the aqueous and ethanolic extracts of Neem (Azadirachta indica) leaves was investigated against 88 clinical isolates of dermatophytes by agar dilution. The isolates included Microsporum canis (50), M.audouinii (5), Trichophyton rubrum (6), Tmentagrophytes (5), T.violaceum (12), T.simii (5) T.verrucosum (1) T.soudanense (l), T.erinacei(1) and Epidermophyton floccosum (2). The results were compared with the minimal inhibitory concentrations of ketoconazole. The ethanolic extract was found to be more active inhibiting 90% (MIC 90) of the isolates at a concentration of 100 ug/ml. The MIC 50s and MIC 90s of the aqueous extract were 500 and > 500 ug/ml whereas the values for ketoconazole were 1 and 2.5 ug/ml respectively.


How to cite this article:
Pankajalakshmi, Venugopal V, Taralakshmi, Venugopal V. Antidermatophytic activity of neem (Azadirachta indica) leaves in Vitro.Indian J Pharmacol 1994;26:141-143


How to cite this URL:
Pankajalakshmi, Venugopal V, Taralakshmi, Venugopal V. Antidermatophytic activity of neem (Azadirachta indica) leaves in Vitro. Indian J Pharmacol [serial online] 1994 [cited 2021 Sep 25 ];26:141-143
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1994;volume=26;issue=2;spage=141;epage=143;aulast=Pankajalakshmi;type=0