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Year : 1984  |  Volume : 16  |  Issue : 2  |  Page : 87--91

Compatibility of chandonium iodide, a new neuromuscular Blocking agent with intravenous anaesthetic in cats

YV Suri1, KC Mukherjee2, Singh Daljitam3, BN Dhawan4 
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Correspondence Address:
Y V Suri


1. Interaction of chandonium iodide, a new non-depolarizing neuromuscular blocking agent, with intravenous anaesthetic agents like thiopentone, ketamine and etomidate has been studied in cats. 2. The onset and duration of neuromuscular block with chandonium and its reversibility by neostigmine were unaffected by the aneasthetic agents investigated. A signifificandy higher dose of chandonium was required with ketamine to produce 50% block of neuromuscular transmission. 3. Chandonium exhibited atropine like effect on cardiac vagal neuroeffector junction. It had no significant effect on blood pH, pCO2 or pO2 . A significant increase ( P < 0.01) in serum potassium was observed in cats anaesthetised with etomidate prior to administration of chandonium and a significant decrease (P < 0.05) was observed with thiopentone anaesthesia.


How to cite this article:
Suri Y V, Mukherjee K C, Daljitam S, Dhawan B N. Compatibility of chandonium iodide, a new neuromuscular Blocking agent with intravenous anaesthetic in cats.Indian J Pharmacol 1984;16:87-91


How to cite this URL:
Suri Y V, Mukherjee K C, Daljitam S, Dhawan B N. Compatibility of chandonium iodide, a new neuromuscular Blocking agent with intravenous anaesthetic in cats. Indian J Pharmacol [serial online] 1984 [cited 2021 Jan 27 ];16:87-91
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1984;volume=16;issue=2;spage=87;epage=91;aulast=Suri;type=0