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Year : 1983  |  Volume : 15  |  Issue : 1  |  Page : 1--66

Abstracts: XV Annual Conference of the Indian Pharmacological Society

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A mixture of two chemically pure glycosides obtained from the stem bark of Symplocos spicata Roxb was studied for pharmacological actions. The glycosides (5 mg/kg, ip) possessed marked relaxant effect (equipotent with the relaxant effect of 10 g/kg, iv adrenaline) on intestine in situ and transient hypotension in anaesthetised dog and moderate relaxant effect on isolated rabbit ileum. The spasmogenic responses of DMPP and acetyl-choline were attenuated by 40% and 55% respectively on isolated guinea-pig ileum. The glycosides had positive inotropic and chronotropic actions on perfused frogSQs heart and a weak curare-like activity on isolated frogSQs rectus abdominis muscle. The glycosides did not have any CNS activity.


How to cite this article:
IPS. Abstracts: XV Annual Conference of the Indian Pharmacological Society.Indian J Pharmacol 1983;15:1-66


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IPS. Abstracts: XV Annual Conference of the Indian Pharmacological Society. Indian J Pharmacol [serial online] 1983 [cited 2020 Nov 24 ];15:1-66
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1983;volume=15;issue=1;spage=1;epage=66;aulast=IPS;type=0