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Year : 1982  |  Volume : 14  |  Issue : 4  |  Page : 301--304

Modification of glibenclamide hypoglycaemia by some antihypertensive agents in rabbits

H Mishra1, B Gupta2, KK Saxena3, VK Kulshreshtha4, DN Prasad5 
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Correspondence Address:
H Mishra


Chlorthalidone (3.0 mg/kg), hydrochlorthiazide (3.0 mg/kg), frusemide (1.0 mg/kg) and clonidine (0.003 mg/kg) did not have any per se effect on fasting blood sugar level of rabbits upto 5 h. when clonidine was administered along with glibenclamide (0.025 mg/k), it not only caused an early onsent of hypo- glycaema but also produced greater fall in blood sugar than that observed with glibenclamide alone. The diuretics did not modify the hypoglycaemic activity of glibenclamide.


How to cite this article:
Mishra H, Gupta B, Saxena K K, Kulshreshtha V K, Prasad D N. Modification of glibenclamide hypoglycaemia by some antihypertensive agents in rabbits.Indian J Pharmacol 1982;14:301-304


How to cite this URL:
Mishra H, Gupta B, Saxena K K, Kulshreshtha V K, Prasad D N. Modification of glibenclamide hypoglycaemia by some antihypertensive agents in rabbits. Indian J Pharmacol [serial online] 1982 [cited 2021 Sep 23 ];14:301-304
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1982;volume=14;issue=4;spage=301;epage=304;aulast=Mishra;type=0