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Year : 1982  |  Volume : 14  |  Issue : 3  |  Page : 273--276

Anti-inflammatory, anticonvulsant and local anaesthetic activity of clonidine A preliminary report

P Jain1, VK Pendse2, KP Singh3, SD Suthar4 
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Correspondence Address:
P Jain


Clonidine, a potent centrally acting antihypertensive drug was screened for anti-inflammatory, anticonvulsant and local anaesthetic activity. In carrageenin-induced inflammation it showed a significant dose dependent anti-inflammatory effect. Clonidine failed to show any anticonvulsant effect against maximal electro-shock convulsions in rats, however it exhibited significant local anaesthetic activity. Diuresis, piloerection and convulsions were observed in higher doses.


How to cite this article:
Jain P, Pendse V K, Singh K P, Suthar S D. Anti-inflammatory, anticonvulsant and local anaesthetic activity of clonidine A preliminary report.Indian J Pharmacol 1982;14:273-276


How to cite this URL:
Jain P, Pendse V K, Singh K P, Suthar S D. Anti-inflammatory, anticonvulsant and local anaesthetic activity of clonidine A preliminary report. Indian J Pharmacol [serial online] 1982 [cited 2020 Nov 28 ];14:273-276
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1982;volume=14;issue=3;spage=273;epage=276;aulast=Jain;type=0