Indian Journal of Pharmacology Home 

RESEARCH PAPER
[Download PDF]
Year : 1981  |  Volume : 13  |  Issue : 4  |  Page : 325--331

Chemical and pharmacological studies on Solanum giganteum jacq

YV Rao1, SK Bandopadhyay2, SB Acharya3, PK Debnath4, T Ganguly5, SN Ganguly6 
1 
2 
3 
4 
5 
6 

Correspondence Address:
Y V Rao


A steroidal alkaloid with an additional-hydroxy and aminogroup was isolated from roots of Solanum giganteum Jacq (N. 0. Solanaceae). The compound decreased spontaneous motor activity and enhanced pentobarbitone hypnosis in albino mice. It produced spasmogenic responses on isolated smooth muscles like rat fundus and oestronised rat uterus and positive inotorpic effect on perfused frog«SQ»s heart. Hypnotic potentiating effect in mice and spasmogenic responses on isolated smooth muscles were blocked by methysergide and BW501 C67 respectively suggesting that the compound possesses serotonin-like activity.


How to cite this article:
Rao Y V, Bandopadhyay S K, Acharya S B, Debnath P K, Ganguly T, Ganguly S N. Chemical and pharmacological studies on Solanum giganteum jacq.Indian J Pharmacol 1981;13:325-331


How to cite this URL:
Rao Y V, Bandopadhyay S K, Acharya S B, Debnath P K, Ganguly T, Ganguly S N. Chemical and pharmacological studies on Solanum giganteum jacq. Indian J Pharmacol [serial online] 1981 [cited 2021 Jan 22 ];13:325-331
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1981;volume=13;issue=4;spage=325;epage=331;aulast=Rao;type=0