Indian Journal of Pharmacology Home 

[Download PDF]
Year : 1978  |  Volume : 10  |  Issue : 3  |  Page : 191--200

Biochemical studies of betel nut constituents

NM Shivapurkar1, SV Bhide2, KJ Ranadive3 

Correspondence Address:
N M Shivapurkar

. To study the biochemical action of different betel nut constituents, aqueous extract and polyphenolic fraction of dried Mangalore betel nut were injected i. p. to Swiss mice and different biochemical parameters viz. nucleic acids, protein, sialic acid and glycogen were measured in liver, lung, kidney and muscle tissues. Arecoline and tannic acid were injected in the same manner for comparison. It was observed that polyphenolic fraction and tannic acid decreased nucleic acid and protein content in almost all the tissues. Both of them decreased glycogen and increased sialic acid in lung and kidney tissues. Many carcinogens behave similarly but the above reported changes may be merely a manifestation of the subtle toxic effects exerted by these extracts. In-depth studies on the various metabolic parameters may help to locate their precise mode of action.

How to cite this article:
Shivapurkar N M, Bhide S V, Ranadive K J. Biochemical studies of betel nut constituents.Indian J Pharmacol 1978;10:191-200

How to cite this URL:
Shivapurkar N M, Bhide S V, Ranadive K J. Biochemical studies of betel nut constituents. Indian J Pharmacol [serial online] 1978 [cited 2023 Mar 27 ];10:191-200
Available from:;year=1978;volume=10;issue=3;spage=191;epage=200;aulast=Shivapurkar;type=0