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Year : 1978  |  Volume : 10  |  Issue : 2  |  Page : 135--138

Hypercholesterolemic effect of angiotensin

KN Singh1, RK Mittal2, V Mishra3, V Chandra4 
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Correspondence Address:
K N Singh


. Angiotensin II administered i.c.v. resulted in a significant increase in blood cholesterol level in dogs. The hypercholesterolemic effect of angiotensin was not observed in bilaterally vagotomized or in hepatectomized dogs. It is suggested that centrally administered angiotensin exerts its effect on liver through vague. It is possible that i.c.v. administration of angiotensin inhibits the vagal centre in the CNS which brings about an increase in blood cholesterol level.


How to cite this article:
Singh K N, Mittal R K, Mishra V, Chandra V. Hypercholesterolemic effect of angiotensin.Indian J Pharmacol 1978;10:135-138


How to cite this URL:
Singh K N, Mittal R K, Mishra V, Chandra V. Hypercholesterolemic effect of angiotensin. Indian J Pharmacol [serial online] 1978 [cited 2021 Jan 15 ];10:135-138
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1978;volume=10;issue=2;spage=135;epage=138;aulast=Singh;type=0