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Year : 1977  |  Volume : 9  |  Issue : 3  |  Page : 215--220

Phenothiazines as histamine and serotonin antagonists without sedation: Part I

Singh Vijai1, HL Sharma2, VN Sharma3 
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Correspondence Address:
Singh Vijai


A series of 10-N-acylamino phenothiazines possessing tertiary butylamino group in their side chain, showed antihistaminic. antispasmodic and antiserotoninergic activity. On comparison with promethazine HCI diphenhydramine HCI and cyproheptadine, the compounds of this series were found feeble in potency but less toxic. All the test compounds were devoid of central nervous system depressant activity.


How to cite this article:
Vijai S, Sharma H L, Sharma V N. Phenothiazines as histamine and serotonin antagonists without sedation: Part I.Indian J Pharmacol 1977;9:215-220


How to cite this URL:
Vijai S, Sharma H L, Sharma V N. Phenothiazines as histamine and serotonin antagonists without sedation: Part I. Indian J Pharmacol [serial online] 1977 [cited 2020 Nov 25 ];9:215-220
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1977;volume=9;issue=3;spage=215;epage=220;aulast=Vijai;type=0