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Year : 1977  |  Volume : 9  |  Issue : 3  |  Page : 203--206

Pressor response to antihistaminics in chicken

SS Yadav1, A Ahmad2 
1 
2 

Correspondence Address:
S S Yadav


Promethazine hydrochloride and diphenhydramine hydrochloride, showed a marked and sustained rise in blood pressor in phenobarbitone anaesthetized WLH chickens which is contrary to the effects in mammals. Pressor effect was not blocked by alpha or beta adrenergic receptor blocking agents. Pretreatment with two doses each of alphamethyl-para-tyrosine and reserpine did not affect the pressor effect of antihistamines. However birds pm-treated with higher doses of reserpine (10 mg/kg daily for two days) showed a marked decrease in pressor response to promethazine. The findings suggest that the pressor response to antihistaminics in chicken is probably mediated through the release of catecholamines.


How to cite this article:
Yadav S S, Ahmad A. Pressor response to antihistaminics in chicken.Indian J Pharmacol 1977;9:203-206


How to cite this URL:
Yadav S S, Ahmad A. Pressor response to antihistaminics in chicken. Indian J Pharmacol [serial online] 1977 [cited 2020 Nov 24 ];9:203-206
Available from: https://www.ijp-online.com/article.asp?issn=0253-7613;year=1977;volume=9;issue=3;spage=203;epage=206;aulast=Yadav;type=0