| DRUG WATCH |
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| Year : 2017 | Volume
: 49
| Issue : 1 | Page : 127-129 |
Chronic lithium intoxication: Varying electrocardiogram manifestations
Raja Naga Mahesh Maddala1, AJ Ashwal2, M Sudhakar Rao2, R Padmakumar2
1 Department of Medicine, Manipal University, Manipal, Udupi, Karnataka, India
2 Department of Cardiology, KMC, Manipal University, Manipal, Udupi, Karnataka, India
Correspondence Address:
M Sudhakar Rao
Department of Cardiology, KMC, Manipal University, Manipal, Udupi, Karnataka
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijp.IJP_204_16
Lithium is a commonly used drug in psychiatric practice. It is used in the treatment of depression and bipolar disorder. It has a narrow therapeutic index with documented adverse effects even near therapeutic levels. It has myriad of manifestations at toxic levels. The cardiovascular effects range from relatively benign ST-T wave changes to fatal arrhythmias. We describe a case of lithium toxicity which presented as a junctional rhythm and later showed a variety of manifestations such as complete heart block, atrial fibrillation, sinus bradycardia, and finally reverted to sinus rhythm at par with serum lithium levels.
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