| DRUG WATCH |
|
| Year : 2012 | Volume
: 44
| Issue : 5 | Page : 654-655 |
Gynecomastia caused by ethionamide
Parveen K Sharma1, Rekha Bansal2
1 Department of Pharmacology, Dr. RP Govt. Medical College, Kangra at Tanda, Himachal Pradesh, India
2 Department of Pulmonary Medicine, Dr. RP Govt. Medical College, Kangra at Tanda, Himachal Pradesh, India
Correspondence Address:
Parveen K Sharma
Department of Pharmacology, Dr. RP Govt. Medical College, Kangra at Tanda, Himachal Pradesh
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.100408
A 43 year old male patient, known case of multidrug resistant tuberculosis, was prescribed antitubercular drugs: kanamycin, levofloxacin, ethionamide, terizidone, Para-Aminosalicylate Sodium (PAS), pyrazinamide and pyridoxine. After 4 months of treatment, the patient developed a lump in the right breast which was approximately around 3 × 3 cm in size, tender on palpation, and not fixed to the underlying tissues. Ultrasonography (USG) revealed a hypoechoic mass of size 2.5 × 0.92 × 2.6 cm in the right breast region behind the nipple without any infiltration to the deeper structures. Gynecomastia due to ethionamide was suspected and the patient was advised anti-inflammatory drugs for 5 days without any change in drug therapy. The pain subsided; however, the nodule remained. Treatment was continued without any change till the patient stopped using the drugs on his own and without doctor's consent. Within a week of stopping of treatment the nodule also disappeared.
[FULL TEXT] [PDF]*
|
