Azathioprine induced cholestatic hepatitis

Viju Moses; Banumathi Ramakrishna; Kurien Thomas

doi:10.4103/0253-7613.89840

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DRUG WATCH

Year : 2011 | Volume : 43 | Issue : 6 | Page : 733-735

Azathioprine induced cholestatic hepatitis

Viju Moses¹, Banumathi Ramakrishna², Kurien Thomas¹
¹ Department of Medicine, Christian Medical College and Hospital, Vellore- 632 004, India
² Department of General Pathology, Christian Medical College and Hospital, Vellore- 632 004, India

Correspondence Address:
Viju Moses
Department of Medicine, Christian Medical College and Hospital, Vellore- 632 004
India

Source of Support: None, Conflict of Interest: None

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DOI: 10.4103/0253-7613.89840

We report a case of cholestatic hepatitis developed one week after exposure to azathioprine. The subsequent prolonged cholestatic phase was followed by full clinical remission. Current knowledge on pathogenesis and epidemiology and the diagnostic challenges presented by this rare complication are discussed, followed by recommendations for monitoring and management.

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Online since 20^th July '04

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