| DRUG WATCH |
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| Year : 2011 | Volume
: 43
| Issue : 5 | Page : 609-610 |
Piperacillin-tazobactam-induced hypokalemia and metabolic alkalosis
Syed Ahmed Zaki1, Vijay Lad2
1 Department of Pediatrics, Lokmanya Tilak Municipal General Hospital and Medical College, Sion, Mumbai 400 022, India
2 Resident in Pediatrics, Lokmanya Tilak Municipal General Hospital and Medical College, Sion, Mumbai 400 022, India
Correspondence Address:
Syed Ahmed Zaki
Department of Pediatrics, Lokmanya Tilak Municipal General Hospital and Medical College, Sion, Mumbai 400 022
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.84986
Piperacillin/tazobactam is a commonly prescribed antibiotic and is generally considered safe. We report a case of a 2-year-old girl who developed hypokalemic metabolic alkalosis and bradycardia after receiving intravenous piperacillin-tazobactam for bronchopneumonia. Upon withdrawal of the drug, serum potassium normalized in 2 days. Hypokalemia is a serious adverse effect of piperacillin-tazobactam and should be suspected while treating patients with this drug. Early recognition and prompt withdrawal of the drug will result in lesser morbidity.
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