SHORT COMMUNICATION |
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Year : 2010 | Volume
: 42
| Issue : 6 | Page : 412-415 |
Therapeutic misadventure with paracetamol in children
So Shivbalan, Malathi Sathiyasekeran, Kuruvilla Thomas
Sundaram Medical Foundation, Dr. Rangarajan Memorial Hospital, Shanthi Colony, IV Avenue Annanagar, Chennai 600 040, India
Correspondence Address:
So Shivbalan Sundaram Medical Foundation, Dr. Rangarajan Memorial Hospital, Shanthi Colony, IV Avenue Annanagar, Chennai 600 040 India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0253-7613.71894
Paracetamol (acetaminophen), though considered a safe, "over the counter" analgesic and antipyretic, can cause liver injury with overdose. Therapeutic misadventure is a unique problem where the existing nomogram used for acute poisoning is not applicable. In this context, early initiation of N-acetylcysteine even before a biochemical evidence of liver injury may be beneficial. A series of 6 children with this type of paracetamol overdose are presented here to increase the awareness and understanding of this problem since no such data is available from India.
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