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Year : 1994  |  Volume : 26  |  Issue : 4  |  Page : 282-287

Drug utilization of antimicrobials in the in-patient setting of a tertiary Hospital

Correspondence Address:
M V Srishyla

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Antimicrobial prescribing pattern was surveyed in the in-patient setting of a 800-bedded tertiary hospital. The prescribing was assessed on the basis of type of use, speciality, site of infection, route of administration and the antimicrobial agent used. The study sample included 556 in-patients at the St. John's Medical College Hospital, Bangalore. The study showed that 56% of in-patients were prescribed antimicrobial agents and 44% of them received a combination of antimicrobials. In all, 36 different antimicrobial agents were prescribed. Gentamicin (17%), metronidazole (9%) and ciprofloxacin (8%) were the most commonly used agents. Lower respiratory tract infection was the most common. The type of use was empirical in 34%, directed in 27% and prophylactic in 32% of the prescriptions. Of the prophylactic prescriptions, 80% were for surgical prophylaxis and 61% of these were administered by oral route. Also, the duration of administration exceeded 72 hours in 92% of the patients prescribed antimicrobials for surgical prophylaxis. The study findings called for a review of antimicrobial prescribing practices.


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