IPSIndian Journal of Pharmacology
Home  IPS  Feedback Subscribe Top cited articles Login 
Users Online : 407 
Small font sizeDefault font sizeIncrease font size
Navigate Here
 »   Next article
 »   Previous article
 »   Table of Contents

Resource Links
 »   Similar in PUBMED
 »  Search Pubmed for
 »  Search in Google Scholar for
 »Related articles
 »   Citation Manager
 »   Access Statistics
 »   Reader Comments
 »   Email Alert *
 »   Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded102    
    Comments [Add]    

Recommend this journal


Year : 1994  |  Volume : 26  |  Issue : 1  |  Page : 52-54

Antagonistic effects of several adrenergic blocking agents on ventricular Tachycardia induced by benzene and adrenaline in rat

Correspondence Address:
G P Thomas

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

Several adrenergic antagonists such as phenoxybenzamine and phentolamine (non-specific alpha), prazosin (alpha1), yohimbine (alpha2), propranolol (non-specific beta with membrane stabilizing action), practolol (cardioselective beta), sotalol (non selective beta with no membrane stabilizing action) and labetalol (non selective beta with alpha1 blocking action) were studied for their effects on ventricular tachycardias induced by benzene and adrenaline in anaesthetised rats. All the alpha and beta adrenergic blocking agents examined showed significant antiarrhythmic effect in this model. The relative potencies of alpha blockers were: prazosin > yohimbine > phenoxybenzamine > phentolamine while that of beta blockers were:labetalol > propranolol > practolol > sotalol.


Print this article     Email this article

Site Map | Home | Contact Us | Feedback | Copyright and Disclaimer | Privacy Notice
Online since 20th July '04
Published by Wolters Kluwer - Medknow