| RESEARCH PAPER
|Year : 1984 | Volume
| Issue : 2 | Page : 99-101
Activities of glucose 6 phosphate and sorbitol dehydrogenases in alloxan induced cataract: an experimental study
UM Rawal, DN Gandhi
1. Decrease in the activity of glucose 6 phosphate dehydrogenase (G6PDH), sorbitol dehydrogenase (SDH) and NADP has been suggested as a possible cause of cataract formation, via the effects on glycolysis, HMP shunt and sorbitol pathways in galactosemic and other types of cataract
2. In contrast to normal lenses alloxan-induced cataractous lenses showed a decrease in the activities of G 6 PDH and SDH in blood, aqueous humor and lens.
3. The results indicate that aloxan-induced cataract has an inhibitory effect on some of the lenticubr metabolic pathways.
U M Rawal
Source of Support: None, Conflict of Interest: None