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Year : 1978  |  Volume : 10  |  Issue : 4  |  Page : 271-275

Drug induced by catalepsy as influenced by apomorphine, methamphetamine, atropine, imipramine, cyproheptadine and promethazine

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S Bala

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. The cataleptic states were produced in rats by morphine, chlorpromazine, trifluoperazine, thioridazine and haloperidol. Morphine catalepsy was readily antagonised by apomorphine but was not blocked by atropine. Methamphetamine, imipramine and atropine significantly antagonised the neuroleptic induced catalepsy. Promethazine could only antagonise the catalepsy induced by haloperidol and thioridazine. The anticataleptic effects of atropine and cyproheptadine against all cataleptogens used were insignificant.


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