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Figure 5: The effect of chronic Celastrus paniculatus oil treatment on reference memory in radial arm maze task. (a) The number of reference memory errors during acquisition of the radial arm maze task across trials; (b) reference memory errors in block 7 and 8 (reference memory errors). Data are represented as mean ± standard error of the mean. NC: Normal control (n = 14). ST: Rats subjected to restraint stress for 21 days (6 h/day) (n = 8). ST + VE (n = 8), ST + CP-400 (n = 8), and ST + CP-600 (n = 8): Stressed rats subjected to 14 days of treatment with vehicle, Celastrus paniculatus 400 or 600 mg/kg, intraperitoneally, respectively. One-way ANOVA followed by Tukey's post hoc test. ***P < 0.001 normal versus stress. ###P < 0.001 stress versus stress + drug treatment

Figure 5: The effect of chronic <i>Celastrus paniculatus</i> oil treatment on reference memory in radial arm maze task. (a) The number of reference memory errors during acquisition of the radial arm maze task across trials; (b) reference memory errors in block 7 and 8 (reference memory errors). Data are represented as mean ± standard error of the mean. NC: Normal control (<i>n</i> = 14). ST: Rats subjected to restraint stress for 21 days (6 h/day) (<i>n</i> = 8). ST + VE (<i>n</i> = 8), ST + CP-400 (<i>n</i> = 8), and ST + CP-600 (<i>n</i> = 8): Stressed rats subjected to 14 days of treatment with vehicle, Celastrus paniculatus 400 or 600 mg/kg, intraperitoneally, respectively. One-way ANOVA followed by Tukey's <i>post hoc</i> test. ***<i>P</i> < 0.001 normal versus stress. ###<i>P</i> < 0.001 stress versus stress + drug treatment