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Figure 1: (a) A healthy liver tissue from a rabbit on distilled water (group 1), clear portal area, portal or hepatic vein and bile duct are observed (H and E, power ×10). (b) A liver tissue from a rabbit treated with paracetamol (group 2). Portal inflammation around the bile duct and portal vein, sinusoidal dilatation also detected (H and E, power ×40). (c) A liver tissue from a rabbit receiving carvedilol followed by paracetamol (group 3), the hepatic vein, central vein and the surrounding area appear normal only with mild sinusoidal dilatation (H and E, power ×10)

Figure 1: (a) A healthy liver tissue from a rabbit on distilled water (group 1), clear portal area, portal or hepatic vein and bile duct are observed (H and E, power ×10). (b) A liver tissue from a rabbit treated with paracetamol (group 2). Portal inflammation around the bile duct and portal vein, sinusoidal dilatation also detected (H and E, power ×40). (c) A liver tissue from a rabbit receiving carvedilol followed by paracetamol (group 3), the hepatic vein, central vein and the surrounding area appear normal only with mild sinusoidal dilatation (H and E, power ×10)