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Figure 4: Effect of n-butyl-β-D-fructofuranoside on cell cycle distribution in Bel-7402 cells. (a) After Bel-7402 cells were treated with n-butyl-β-D-fructofuranoside (0, 50 and 75μg/ml) for 48 hours, the cells were stained with propidium iodide, and the DNA contents were analyzed using flow cytometry. The 2N (diploid) and 4N (tetraploid) DNA contents represent the G1and G2/M phases, respectively, of the cell cycle. M1 indicate the percentage of apoptotic sub-G1 cells with hypodiploid DNA content. (b) The percentage of cells in different phases of cell cycle was represented by bar chart. Data are presented as means ± SD (n = 3). The asterisk indicates a significant difference between control and drug-treated cells (*P < 0.05)

Figure 4: Effect of n-butyl-β-D-fructofuranoside on cell cycle distribution in Bel-7402 cells. (a) After Bel-7402 cells were treated with n-butyl-β-D-fructofuranoside (0, 50 and 75μg/ml) for 48 hours, the cells were stained with propidium iodide, and the DNA contents were analyzed using flow cytometry. The 2N (diploid) and 4N (tetraploid) DNA contents represent the G1and G2/M phases, respectively, of the cell cycle. M1 indicate the percentage of apoptotic sub-G1 cells with hypodiploid DNA content. (b) The percentage of cells in different phases of cell cycle was represented by bar chart. Data are presented as means ± SD (<i>n</i> = 3). The asterisk indicates a significant difference between control and drug-treated cells (*<i>P</i> < 0.05)