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Figure 3: Response induced by intra-central amygdala (CeA) microinjection of L-arginine (0.3-3 μg/rat) prior to naloxone injection (0.4 mg/kg, intraperitoneally) before testing of morphine-induced conditioning. The cumulative response was measured 10 min later. The control group though passed all the procedure but only received saline (1 μL/rat, intra-CeA) instead of L-arginine. Data are expressed as count of behavioral signs/15 min ± standard error of mean. *P < 0.05 difference compared to the control

Figure 3: Response induced by intra-central amygdala (CeA) microinjection of L-arginine (0.3-3 μg/rat) prior to naloxone injection (0.4 mg/kg, intraperitoneally) before testing of morphine-induced conditioning. The cumulative response was measured 10 min later. The control group though passed all the procedure but only received saline (1 μL/rat, intra-CeA) instead of L-arginine. Data are expressed as count of behavioral signs/15 min ± standard error of mean. *<i>P</i> < 0.05 difference compared to the control