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Figure 2: Effect of vildagliptin, metformin, and rosiglitazone (alone and in combination) on liver histology in high fat diet-induced nonalcoholic fatty liver disease in mice (a) Normal control, (b and c) Nonalcoholic fatty liver disease control: profound marked hepatic steatosis and ballooning, (d) vildagliptin (10 mg/kg), (e) metformin (350 mg/kg), (f) rosiglitazone (10 mg/kg), (g) vildagliptin (10 mg/kg) + metformin (350 mg/kg), (h) vildagliptin (10 mg/kg) + rosiglitazone (10 mg/kg): reduced hepatic steatosis and ballooning. H & E staining of liver tissue (×10, 50 μm)

Figure 2: Effect of vildagliptin, metformin, and rosiglitazone (alone and in combination) on liver histology in high fat diet-induced nonalcoholic fatty liver disease in mice (a) Normal control, (b and c) Nonalcoholic fatty liver disease control: profound marked hepatic steatosis and ballooning, (d) vildagliptin (10 mg/kg), (e) metformin (350 mg/kg), (f) rosiglitazone (10 mg/kg), (g) vildagliptin (10 mg/kg) + metformin (350 mg/kg), (h) vildagliptin (10 mg/kg) + rosiglitazone (10 mg/kg): reduced hepatic steatosis and ballooning. H & E staining of liver tissue (×10, 50 μm)