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Figure 4: Histological changes of rat pancreas of islets of langerhans a) Non diabetic normal histological structure of rat pancreas showing normal islet b) Diabetic control rat showing irregular cells, not well defined necrosis of cells is very clear c) Glibenclamide (10 mg/kg. p.o) treated rat pancreas showing mild protection from STZ-induced changes in the pancreatic islets d) MEAV extract (200mg/kg) showed no significant changes in cells were seen when compared with diabetic control e) MEAV (400 mg/kg) showed slight regeneration of β-cells were seen when compared with diabetic control

Figure 4: Histological changes of rat pancreas of islets of langerhans a) Non diabetic normal histological structure of rat pancreas showing normal islet b) Diabetic control rat showing irregular cells, not well defined necrosis of cells is very clear c) Glibenclamide (10 mg/kg. p.o) treated rat pancreas showing mild protection from STZ-induced changes in the pancreatic islets d) MEAV extract (200mg/kg) showed no significant changes in cells were seen when compared with diabetic control e) MEAV (400 mg/kg) showed slight regeneration of β-cells were seen when compared with diabetic control