Indian J Pharm Close
 

Figure 2: Effect of tacrine (TAC; 5 mg/kg po) and rivastigmine (RIVA; 5 mg/kg po) on transfer latency time (TLT) in the PA test to observe the effect on scopolamine (SCO; 3 mg/kg ip) induced impaired (a) acquisition, administered 30 minutes prior to fi rst trial and (b) consolidation, administered fi ve minutes prior to fi rst trial. The maximal time of latency was set at 270s (cutoff time). Values are expressed as mean ± SEM; n = fi ve. *P < 0.05, **P < 0.01 signifi cant increase in TLT on second trial as compared to their respective fi rst trial; student’s (paired) ‘t’ test

Figure 2: Effect of tacrine (TAC; 5 mg/kg po) and rivastigmine (RIVA; 5 mg/kg po) on transfer latency time (TLT) in the PA test to observe the effect on scopolamine (SCO; 3 mg/kg ip) induced impaired (a) acquisition, administered 30 minutes prior to fi rst trial and (b) consolidation, administered fi ve minutes prior to fi rst trial. The maximal time of latency was set at 270s (cutoff time). Values are expressed as mean ± SEM; n = fi ve. *P < 0.05, **P < 0.01 signifi cant increase in TLT on second trial as compared to their respective fi rst trial; student’s (paired) ‘t’ test