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Year : 2002  |  Volume : 34  |  Issue : 6  |  Page : 409--415

Anti-hyperglycaemic activity of cassia Kleinii leaf extract in glucose fed normal rats and alloxan-induced diabetic rats

V Babu1, T Gangadevi2, A Subramoniam3 
1 
2 
3 

Correspondence Address:
V Babu


Objective: The efficacy of ivermectin pour on formulation (Ivomec pour on) against gastrointestinal nematodiasis in cattle ( Bos indicus), its effect on the blood parameters and the live weight gain of the host was investigated. Methods: The cattle harbouring the gastrointestinal nematodes were treated with ivermectin pour on formulation at the dose rate of 500 (g/kg body weight topically along the back line. The faecal samples and blood parameters were investigated at day 0,7,14, 21 and 28 post treatment, and live body weight gain was evaluated at day 0 and 28 post treatment. Results: Ivermectin pour on formulation was found to be 100% effective against gastrointestinal nematodes in cattle. After 28 days of treatment both haemoglobin and PCV values were significantly increased while ESR was significantly decreased after 14 days of treatment. Body weight of cattle was increased by 6.25% after 28 days of treatment. Conclusion: Gastrointestinal nematodiasis in cattle can be treated successfully with ivermectin pour on formulation. The drug has direct influence on blood parameter and live weight gain of the treated animals. Ivermectin may be useful as an anthelmintic of continued relevance.


How to cite this article:
Babu V, Gangadevi T, Subramoniam A. Anti-hyperglycaemic activity of cassia Kleinii leaf extract in glucose fed normal rats and alloxan-induced diabetic rats.Indian J Pharmacol 2002;34:409-415


How to cite this URL:
Babu V, Gangadevi T, Subramoniam A. Anti-hyperglycaemic activity of cassia Kleinii leaf extract in glucose fed normal rats and alloxan-induced diabetic rats. Indian J Pharmacol [serial online] 2002 [cited 2019 Nov 18 ];34:409-415
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=2002;volume=34;issue=6;spage=409;epage=415;aulast=Babu;type=0