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Year : 1999  |  Volume : 31  |  Issue : 2  |  Page : 124--127

The effect of panax ginseng and diazepam on norepinephrine levels of whole brain and hypothalamus during stress

D Bhattacharyya1, TK Sur2 
1 
2 

Correspondence Address:
D Bhattacharyya


Objective: To see the effect of anti-stress agents like Panax ginseng and diazepam on stress-induced elevation of norepinephrine (NE) in brain and hypothalamus of rats. Methods: NE was estimated in brain and hypothalamus of rats by spectrophotofluorimetry. Plasma corticosterone was measured by fluorimetry. Results: Panax ginseng and diazepam both per se did not modify NE levels of brain and hypothalamus in unstressed rats. But both the drugs attenuated stress-induced elevation of NE of brain and hypothalamus and simultaneously attenuated stress-induced elevation of plasma corticosterone. Conclusion: Anti-stress effect of Panax ginseng and diazepam seems to be mediated through attenuation of levels of NE in brain and hypothalamus.


How to cite this article:
Bhattacharyya D, Sur T K. The effect of panax ginseng and diazepam on norepinephrine levels of whole brain and hypothalamus during stress.Indian J Pharmacol 1999;31:124-127


How to cite this URL:
Bhattacharyya D, Sur T K. The effect of panax ginseng and diazepam on norepinephrine levels of whole brain and hypothalamus during stress. Indian J Pharmacol [serial online] 1999 [cited 2020 Feb 27 ];31:124-127
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1999;volume=31;issue=2;spage=124;epage=127;aulast=Bhattacharyya;type=0