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Year : 1995  |  Volume : 27  |  Issue : 3  |  Page : 167--170

Effect of nifedipine and aspirin on platelet aggregation: A study in hypertensive patients and normal volunteers

AA Desai1, VK Nayak2, NK Desai3, KC Gupta4 
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Correspondence Address:
A A Desai


We studied the pattern of platelet aggregation in normal subjects as well as in patients of essential hypertension. Our study revealed that platelet aggregation was enhanced in hy-pertensive patients as compared to normal healthy volunteers. Both nifedipine (10 mg) and aspirin (75 mg) inhibited the platelet aggregation when administered alone or in combination both in hypertensive patients and in normal subjects. The combination of these two drugs might be of importance in routine use for essential hypertension for the combined effect of controlling the hypertension by nifedipine and inhibiting platelet aggregation by both nifedipine and aspirin.


How to cite this article:
Desai A A, Nayak V K, Desai N K, Gupta K C. Effect of nifedipine and aspirin on platelet aggregation: A study in hypertensive patients and normal volunteers.Indian J Pharmacol 1995;27:167-170


How to cite this URL:
Desai A A, Nayak V K, Desai N K, Gupta K C. Effect of nifedipine and aspirin on platelet aggregation: A study in hypertensive patients and normal volunteers. Indian J Pharmacol [serial online] 1995 [cited 2020 Jan 22 ];27:167-170
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1995;volume=27;issue=3;spage=167;epage=170;aulast=Desai;type=0