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Year : 1994  |  Volume : 26  |  Issue : 4  |  Page : 304--306

Lack of genotoxicity of omeprazole in chromosomal aberration and sisterChromatid exchange assays using cultured human lymphocytes in vitro

TS Kumaravel1, Lakshmi Karthika2, P Balakrishnamurthy3 
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Correspondence Address:
T S Kumaravel


Omeprazole was tested in chromosomal aberration (CA) and sister chromatid exchange (SCE) assays using cultured human lymphocytes in vitro. While CA is a standard battery of test system in mutagenicity studies, SCE is considered to be the most simple reliable and sensitive index of DNA damage/repair. Omeprazole was found to be non toxic in both these tests.


How to cite this article:
Kumaravel T S, Karthika L, Balakrishnamurthy P. Lack of genotoxicity of omeprazole in chromosomal aberration and sisterChromatid exchange assays using cultured human lymphocytes in vitro.Indian J Pharmacol 1994;26:304-306


How to cite this URL:
Kumaravel T S, Karthika L, Balakrishnamurthy P. Lack of genotoxicity of omeprazole in chromosomal aberration and sisterChromatid exchange assays using cultured human lymphocytes in vitro. Indian J Pharmacol [serial online] 1994 [cited 2020 Aug 4 ];26:304-306
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1994;volume=26;issue=4;spage=304;epage=306;aulast=Kumaravel;type=0