| [Download PDF]
|Year : 1984 | Volume
| Issue : 4 | Page : 228--230
Pharmacokinetic study of penicillin G and ampicillin in buffalo calves
MK Singh1, C Jayachandran2, NC Banerjee3
I. Plasma concentrations of pencillin G (10,000 iu/kg.) and Ampicillin (6 mg/kg.) (administered intramuscularly) in six buffalo calves were estimated at different time intervals by microbiological.assay.
2. Penicillin G attained a peak concentration of 9.53 ( 1.46 iu/ml. at 15 min. and the therapeutic concentration (Cpther) was maintained for about 5 hr. -3.
3.On the other hand, ampicillin attained its peak concentration of 8.50 ( 1.28 (g/ml at 1 hr and its Cpther, was maintained for about 8 hr.
4. The elimination half-life( t1/2 B) was found to be 1.10 ( 0.20 hr and 1.35 ( 0.32 hr for penicillin G and ampicillin respectively.
M K Singh
|How to cite this article:|
Singh M K, Jayachandran C, Banerjee N C. Pharmacokinetic study of penicillin G and ampicillin in buffalo calves.Indian J Pharmacol 1984;16:228-230
|How to cite this URL:|
Singh M K, Jayachandran C, Banerjee N C. Pharmacokinetic study of penicillin G and ampicillin in buffalo calves. Indian J Pharmacol [serial online] 1984 [cited 2020 Aug 9 ];16:228-230
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1984;volume=16;issue=4;spage=228;epage=230;aulast=Singh;type=0