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Year : 1984  |  Volume : 16  |  Issue : 4  |  Page : 228--230

Pharmacokinetic study of penicillin G and ampicillin in buffalo calves

MK Singh1, C Jayachandran2, NC Banerjee3 
1 
2 
3 

Correspondence Address:
M K Singh


I. Plasma concentrations of pencillin G (10,000 iu/kg.) and Ampicillin (6 mg/kg.) (administered intramuscularly) in six buffalo calves were estimated at different time intervals by microbiological.assay. 2. Penicillin G attained a peak concentration of 9.53 ( 1.46 iu/ml. at 15 min. and the therapeutic concentration (Cpther) was maintained for about 5 hr. -3. 3.On the other hand, ampicillin attained its peak concentration of 8.50 ( 1.28 (g/ml at 1 hr and its Cpther, was maintained for about 8 hr. 4. The elimination half-life( t1/2 B) was found to be 1.10 ( 0.20 hr and 1.35 ( 0.32 hr for penicillin G and ampicillin respectively.


How to cite this article:
Singh M K, Jayachandran C, Banerjee N C. Pharmacokinetic study of penicillin G and ampicillin in buffalo calves.Indian J Pharmacol 1984;16:228-230


How to cite this URL:
Singh M K, Jayachandran C, Banerjee N C. Pharmacokinetic study of penicillin G and ampicillin in buffalo calves. Indian J Pharmacol [serial online] 1984 [cited 2020 Jan 20 ];16:228-230
Available from: http://www.ijp-online.com/article.asp?issn=0253-7613;year=1984;volume=16;issue=4;spage=228;epage=230;aulast=Singh;type=0